The Karolinska Stroke Update series of meetings started in 1996 to discuss recent results from clinical trials on stroke therapy and to consent on their implementation into clinical practice. The consensus statements from the six meetings until 2006 include several treatment strategies within stroke prevention, acute stroke therapy and rehabilitation. From 2008 the meeting will be integrated with the revision of the European Stroke Organisation (ESO) guidelines (previously EUSI guidelines). Karolinska Stroke Update is held bi-annually in Stockholm, Sweden. More than 350 delegates participated in the last Karolinska Stroke Update in 2006.